Propranolol, or propranolol under the brand names Enderal and Hemangiol, is a beta-blocker and prescription drug that affects nerve impulses in certain areas of the body, such as the heart and blood flow to the arteries and veins. As a result, the heart beats more slowly and steadily, and an adequate amount of blood and oxygen is pumped to different parts of the body. In this article, you will learn more about the use of propranolol, how to use it and the side effects of this important drug. Stay with us until the end of the article.
What is Propranolol for?
Propranolol is prescribed in the following cases:
- Panic disorder;
- Treatment of tumors;
- High blood pressure;
- Fundamental vibration;
- Neonatal hemangioma;
- Angina (chest pain);
- Aggressive behaviors;
- Treatment and prevention of heart attack;
- Decreased severity and frequency of migraine headaches;
- Pheochromocytoma, a type of adrenal tumor;
- Restlessness due to antipsychotic drugs;
- Supraventricular arrhythmia (an abnormal rhythm in the upper chambers of the heart).
Propranolol may be used for other purposes. Propranolol is also available as tablets, capsules, oral solution (hemangiol), and solution for injection. Hemangiol (propranolol oral syrup) is prescribed to treat a genetic condition called neonatal hemangioma in infants at least 4 weeks of age. Hemangiomas are tufts of extra blood vessels that commonly occur in the arteries and can develop into sores or red marks on the skin. It can also have serious side effects on organs such as the liver, brain or digestive system.
Important points before taking propranolol
You should not use propranolol in the following cases:
- Drug sensitivity;
- Very weak heart rate that may cause fainting;
- Serious heart problems (such as sick sinus syndrome or AV obstruction).
Consult your doctor before taking propranolol tablets in the following cases:
- Muscle disorder;
- Thyroid disorders;
- Liver or kidney disease;
- Low blood sugar or diabetes;
- Congenital heart failure;
- Low heart rate or blood pressure;
- Pheochromocytoma (adrenal tumor);
- Bronchitis, emphysema and other respiratory disorders;
- Circulatory problems (such as Raynaud’s syndrome).
It is not known whether propranolol has a negative effect on pregnancy or the fetus. If you are pregnant or planning to become pregnant, consult your doctor. Propranolol passes into breast milk and may have an adverse effect on the infant. Be sure to tell your doctor if you are breast-feeding your baby.
How to take propranolol
Follow your doctor’s instructions and prescription to take propranolol. Your doctor may change the dose of the medicine for better results. Avoid taking more or less or for a longer period of time.
- Measure the solution with special scales;
- The dose of propranolol varies from person to person;
- Your blood pressure needs to be checked while you are taking the medicine;
- It takes a few days to a few weeks for the drug to work properly;
- Propranolol capsules usually have a longer duration of action and are taken once a day;
- Propranolol is usually given alone or in combination with other medicines to treat high blood pressure;
- If you are having surgery, tell your surgeon to stop taking propanol for a while;
- You can take propranolol with or without food, but use the same medicine at the same time each time;
- Avoid crushing, chewing, breaking or opening long-release capsules and swallowing them whole;
- This drug may produce unusual results in certain medical tests. Inform your doctor about taking the medicine;
- Propranolol is only part of a high blood pressure treatment program and you need to do other things like diet, exercise and weight control;
- Do not forget the dose of the medicine and do not stop taking propranolol abruptly. Abrupt discontinuation of the drug may make your condition worse. Follow your doctor’s instructions for reducing the dose;
- If you are using propranolol for high blood pressure, continue taking the medicine while you are recovering. High blood pressure often has no symptoms. You may need to take your blood pressure medicine forever;
- Hemangiol should be given to the baby during or immediately after breastfeeding. Doses should be at least 9 hours apart. Make sure your baby is fed regularly while taking the medicine. Tell your doctor about any changes in your baby’s weight or nausea. The dose of hemangiol for children is based on weight and the dose of the drug changes with each change in the child’s weight.
Forget the dose of propranolol
- For short-acting propranolol: As soon as you are reminded, take the missed dose. If less than 4 hours remain until the next dose, skip the missed dose;
- For long-term release propranolol: Take the missed dose as soon as you remember. If the next dose is less than 8 hours left, skip the missed dose;
- From Take extra doses Do not take medication to make up for a forgotten dose.
In case of drug abuse, call the emergency number (115). Side effects of taking propranolol include:
- Slow or irregular heartbeat;
Side effects of propranolol
If any symptoms of an allergic reaction to propranolol including urticaria; Difficulty breathing; If you have swelling of the face, lips, tongue or throat, go to the emergency room immediately. Some of the symptoms of the drug are mild and go away after a few weeks, when the body gets used to the drug. Any severe symptoms or any symptoms that do not go away over time should be reported to your doctor. The person may have taken too much medicine or their body may not have responded well to the medicine.
See your doctor in the following cases:
- Slow or irregular heartbeat;
- Depression, confusion, hallucinations;
- Sleep problems or nightmares;
- Feeling cold in the arms and legs;
- Chest tightness or difficulty breathing;
- Feeling light-headed or fainting;
- Shortness of breath (even with a little struggle), swelling, rapid weight gain;
- Sudden weakness, vision problems, or loss of balance (especially in a child with hemangiomas of the face and head);
- Low blood sugar including headache, hunger, weakness, sweating, dizziness, mood swings, dizziness, rapid heartbeat or feeling angry;
- Liver problems include nausea, upper stomach pain, itching, tiredness, loss of appetite, dark urine, gray stools, jaundice;
- Severe skin reactions include fever, sore throat, swelling of the face or tongue, eye irritation, skin pain with red or purple pimples that spread especially to the face and upper body and cause blisters or scaling;
- Decreased blood sugar in the child including pale skin, blue or blue skin, sweating, noise, crying, not eating food, feeling cold, drowsiness, poor or shallow breathing (possibility of shortness of breath for a short time), seizures, loss of consciousness.
Common side effects of propranolol
Common side effects of propranolol include:
- Nausea, vomiting, diarrhea, constipation, constipation;
- Decreased libido, inability or difficulty in orgasm;
- Sleep problems (insomnia);
- feeling exhausted;
- Symptoms of bronchitis;
- Dry eyes;
- hair loss.
These are the most common side effects of the drug and not all.
Drug Interaction Propranolol
Switching from other antihypertensive drugs, such as clonidine, to propranolol should be done slowly and increase the dose of propranolol over a few days by reducing the dose. Propranolol is a beta blocker and should not be used with other drugs in this family. Combining these drugs together may keep your heart rate to a minimum. Also, propranolol should not be used with A. blockers. سی. (ACE) used calcium channel blockers and alpha blockers that have similar functions.
Talk to your doctor about all the medications you are taking and any medications you have started or stopped taking with propranolol. Important drugs include the following:
- Steroid drugs (such as prednisone);
- Blood thinners (such as warfarin, camodin, and jantown);
- Antidepressants (such as amitriptyline, clomipramine, imipramine);
- Cardiac or blood pressure medication (such as amiodarone, diltiazem, propafenone, quinidine, verapamil);
- Medication to treat high blood pressure or prostate disorder (eg dexazosin, prazosin, trazosin);
- Nonsteroidal anti-inflammatory drugs (NSAIDs) (eg aspirin, ibuprofen, naproxen, celecoxib, diclofenac, indomethacin, meloxicam).
These are not a complete list of medications. Other over-the-counter medications, vitamins, and herbal products may interact with propranolol.
Because of the side effects and risks of propranolol, many people use alternative medicines to get rid of the symptoms.
- Metoprolol can be used as a selective beta blocker with fewer respiratory side effects in people with cardiovascular problems who are concerned about the health of their respiratory system.
- Because propranolol is used to prevent tremors and migraines. It is difficult to provide alternatives that are suitable for each use. It is better for patients to consult a doctor to introduce a suitable alternative.
- Do not share your medications with others;
- Keep medicines out of the reach of children;
- Avoid alcohol. Alcohol may increase your blood propranolol levels;
- Store the medicine at room temperature away from moisture and heat. Avoid freezing the soluble drug. Discard the hemangiol 2 months after opening;
- Do not get up quickly from a sitting or lying position or when you feel dizzy. Get up slowly and hold yourself to prevent falling.
Propranolol brand names in Iran
The following are some of the propranolol brand names in Iran:
- Pranol ampoule 1 mg Pharmaceutical drug production;
- Propratud 40 mg tablet made by Tehran Daroo Pharmacy;
- Propranolol-Obaidi 20 mg tablets made by Obaidi Pharmacy;
- Pranol tablets 10, 20, 40 and 80 mg Pharmaceutical drug production.
Answers to Frequently Asked Questions About Propranolol
Does propranolol help treat mental disorders?
Negative emotions play an important role in mental disorders such as post-traumatic stress disorder. A new study found that propranolol could be a good drug to help people with mental disorders and anxiety. If taken before a recollection of an event, it can prevent emotional memories and somehow impair emotional memory; Therefore, a person’s emotional dependence on negative emotions may not be very strong and helps the person to overcome negative emotions or a terrible event. Another study showed that this group of people with propranolol use have a better ability to think.
Can propranolol be available over-the-counter?
No. Propranolol is a prescription drug and must be prescribed by a doctor.
How long does propranolol take to work?
It takes about 30 to 60 minutes for the drug to take effect. Most people take propranolol 1 hour before each stressful event.
How much propranolol should be taken in a stressful situation?
Propranolol is available in 10, 40, 80 and 160 mg tablets. The standard dose for anxiety situations is 10 to 80 mg. Of course, like any other medicine, the dose of the medicine is determined by the doctor based on the symptoms, body weight and response to the medicine.
Can propranolol be used only when needed?
Yes. Many people use propranolol before major events, public speaking, meetings, and other stressful situations. However, if you are using this medicine for a specific disease, be sure to follow your doctor’s instructions.
Is Propranolol Addictive?
Propranolol is not an addictive drug, but you may get used to it; Especially if you are under a lot of stress.
How familiar are you with Pranol tablets and what are you using them for? If you wish, you can share your experience and opinion with us in the comments section. Also, you can send this article to your friends through social networks to learn more about propranolol.