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Everything about Diphenhydramine; From how to use to side effects and drug interactions

Study guide




Diphenhydramine under the brand name Benadryl is a type of antihistamine that reduces the effect of natural histamine in the body and is used to relieve symptoms such as skin irritation, itching, watery eyes, itchy eyes and nose and throat, cough, runny nose and sneezing. . In this article, we try to learn more about Diphenhydramine, its uses and side effects, and answer 10 common questions about this drug. Stay with us until the end of the article.

Uses of Diphenhydramine

Diphenhydramine Hydrochloride is an antihistamine that inhibits a specific natural substance called histamine that is produced during an allergic reaction. Diphenhydramine also dries out runny eyes and nose by inhibiting other natural substances produced by the body (such as acetylcholine). Diphenhydramine is usually given in the following cases:

  • Relaxation and sleep;
  • Treatment of specific symptoms of Parkinson’s disease;
  • Symptoms of allergies, diarrhea and colds;
  • Prevention and treatment of nausea, vomiting and diarrhea related to motion sickness.

Important points before taking Diphenhydramine

  • From diphenhydramine to put the baby to sleep Do not use.
  • After taking the drug, do not do things that require full awareness or vision.
  • Diphenhydramine to treat or reduce the duration of colds It is not and may have serious side effects.
  • Diphenhydramine may contain some sugar or aspartame. Be sure to tell your doctor if you have diabetes, liver disease, phenylketonuria, or any other condition that you should limit or stop consuming sugar.
  • Be sure to tell your doctor and pharmacist if you are allergic to diphenhydramine or any other medicine. These may contain inactive elements that can cause an allergic reaction or other problems.
  • These products do not seem to be suitable for relieving the symptoms of cough and cold in children under 6 years of age and may lead to death. Therefore, do not use diphenhydramine for this age group without a doctor’s prescription. Diphenhydramine capsules and tablets are not suitable for children under 12 years of age and consult your doctor.
  • Be sure to tell your doctor or pharmacist if you have any of the following conditions:
    • Convulsions;
    • Hyperthyroidism;
    • Heart problems;
    • High or low blood pressure;
    • Liver or kidney disease;
    • High eye pressure (glaucoma);
    • If potassium is used;
    • Gastrointestinal problems (such as ulcers or obstruction);
    • Respiratory problems (such as asthma, emphysema, or chronic obstructive pulmonary disease);
    • Difficulty urinating (for example, due to an enlarged prostate or bladder obstruction).

How to take Diphenhydramine

Follow your doctor’s prescription and instructions on the medicine package and ask your doctor or pharmacist if you have any questions.

  • Diphenhydramine tablets, capsules or syrup can be taken with or without food;
  • Use standard dosages to use diphenhydramine syrup. You can get these scales from the pharmacy;
  • When using fast-dissolving tablets, you should allow enough time for it to dissolve in the mouth and on the tongue, and then swallow the tablet with or without water, and if your tablet is chewable, be sure to chew it and then swallow it.

Dosage of Diphenhydramine

The dose of the drug depends on your age, illness and response to treatment. Diphenhydramine has different brands, and the amount of drug may be different in each. For this reason, be sure to read the information on the package before taking the medicine. Do not take more doses or increase the number of times you take it.

  • See your doctor if your symptoms do not improve or get worse with medication;
  • To prevent motion sickness, take the medicine 30 minutes before the start of the trip;
  • To help you fall asleep, take medicine 30 minutes before going to bed. If you still have trouble sleeping after 2 weeks, consult your doctor.

Forget the dose

Diphenhydramine may sometimes be taken at the required time and without a specific schedule. However, if you are taking the medicine as planned, take the missed dose as soon as you remember. If you are close to the next dose, skip the missed dose. Also, avoid taking twice as much medicine.

Drug abuse

If you have a drug abuse problem and symptoms such as fainting or breathing problems, call the emergency number (115) immediately. Other symptoms of drug abuse include:

  • Convulsions;
  • Severe drowsiness;
  • Dilated pupils.
Symptoms of child abuse include mood swings such as restlessness, mood swings, and hallucinations.

Side effects of diphenhydramine

Many people who use Diphenhydramine do not have serious side effects. Remember that your doctor has prescribed Diphenhydramine according to your illness and its side effects. Some of the side effects of Diphenhydramine include:

  • Constipation;
  • Dizziness;
  • Blurred vision;
  • Drowsiness;
  • stomach discomfort;
  • Dry mouth, nose and throat.

Talk to your doctor if any of the symptoms persist or get worse.

To relieve dry mouth, you can suck on candy or pieces of ice, chew gum, or use artificial water or saliva.

If you have any of the following symptoms, talk to your doctor immediately:

  • Convulsions;
  • Difficulty urinating;
  • Fast or irregular heartbeat;
  • Dry mouth, eyes and nose;
  • Psychological and mood changes (including restlessness and confusion).

Serious allergic reactions to this drug are rare. However, if you have any of the following symptoms, go to the emergency room right away:

  • Difficulty breathing;
  • Skin irritation;
  • Severe dizziness;
  • Feeling faint;
  • Itching or swelling (especially on the face, tongue and throat);
  • Cramps in the neck and shoulders and uncontrollable movements of the tongue.
These are not all side effects of the drug. If you have any other side effects, be sure to talk to your doctor.

Drug Diphenhydramine Drug Interaction

Drug interactions may affect drug performance and increase the likelihood of side effects. Make a list of all the ingredients (prescription drugs, over-the-counter and herbal products) and give it to your doctor or pharmacist. Do not start or stop taking any medicine arbitrarily and do not change the dose of the medicine.

The following medications may interact with Diphenhydramine:

  • Topical skin antihistamines such as diphenhydramine cream, ointment or spray;
  • Diphenhydramine may affect the results of certain tests, such as skin sensitivity tests. Therefore, inform your doctor before taking the drug before the test;
  • Use other sleeping pills such as painkillers, cough medicines (such as codeine or hydrocodone), sleeping pills or anxiety medications (such as alprazolam, lorazepam, and zolpidem), muscle relaxants (such as carisoprodol and cyclobenzaprine), or other antihistamines (such as chloramphenicol) and chloramphenicol.

Important points for people with special conditions

  • Children may be more sensitive to the side effects of diphenhydramine, which may increase excitement instead of drowsiness;
  • Diphenhydramine should be used during pregnancy only if needed. Talk to your doctor about the benefits and risks of taking the drug during this time;
  • Older people may be more sensitive to the side effects of the drug, such as drowsiness, dizziness, dizziness, constipation, or difficulty urinating. Drowsiness, dizziness and dizziness increase the likelihood of falling;
  • Diphenhydramine passes through breast milk and may have adverse effects on the infant. It may also slow down the process of breastfeeding. Be sure to consult your doctor if you are taking diphenhydramine before breastfeeding.

important points

  • Keep medicine out of the reach of children and animals;
  • Keep the medicine at room temperature, away from light, moisture and heat;
  • Do not put Diphenhydramine Syrup in the freezer;
  • Talk to your pharmacist about how to dispose of excess medicine and do not throw it in a sewer.

Diphenhydramine brand names in Iran

Here are some Diphenhydramine trade letters in Iran Brought to:

  • Algariz Sirofen from Tehran Daroo;
  • Diphenhydramine Enamel Syrup Enamel Pharmacy;
  • Amy-Diphenhydramine Syrup Amin Pharmacy;
  • 60 ml diaphragm syrup of Kharazmi Pharmacy;
  • Dana Pharmaceutical 25 mg soft gel capsule;
  • Diphenhydramine syrup from the mayor from the pharmacy of the mayor;
  • Diphenhydramine tablets – Containing 25 mg Pharmaceuticals containing;
  • Caspian Diphenhydramine ampoule 50 mg / ml Caspian Pharmacy supply.

Frequently Asked Questions About Using Diphenhydramine

1. What are the disadvantages of Diphenhydramine in the market?

  • Topical gel;
  • Topical cream;
  • Oral tablets;
  • Topical adhesive;
  • Topical spray;
  • Oral chewable tablets;
  • Oral diphenhydramine syrup;
  • Diphenhydramine gel-liquid capsule.

2. What is the difference between topical and oral diphenhydramine products?

Its oral products are in the form of tablets, oral gels and diphenhydramine syrup, which eliminate the symptoms of allergies, especially in the upper part of the respiratory system. The topical type is used for the skin surface and eliminates the symptoms of itching and pain on the skin.

3. Can products similar to Diphenhydramine be used at the same time?

No. Even if one product is oral and the other is topical, two products containing diphenhydramine should not be used at the same time.

4. What is the maximum dose of Diphenhydramine?

The oral form of the drug should not be used more than 6 times a day. The maximum dose for adults and children older than 12 years is 300 mg per day. This amount is a maximum of 150 mg for children 6 to 12 years old.

5. Can topical diphenhydramine be used for pets such as dogs and cats?

No. These products are not designed for animals.

6. Does Diphenhydramine Have Long-Term Side Effects?

Yes. Although long-term side effects of the drug are rare, there may be problems such as: Constipation, Anxiety, Blurred vision, Dependence, Memory problems and Dementia (Especially in the elderly).

7. Does taking diphenhydramine cause depression?

No. Depression is not a common side effect of diphenhydramine. If you get depressed while taking medicine, talk to your doctor.

8. Does diphenhydramine cause weight gain?

Yes. Weight gain is seen in some people. If this worries you, talk to your doctor.

9. Can topical diphenhydramine be used to treat insect bites and stings?

Yes. Topical products of this medicine help to treat pain and itching caused by insect bites.

10. Is Diphenhydramine suitable for the treatment of migraine headaches?

No. Although it may be used in combination with other medications to treat migraine headaches, diphenhydramine does not help improve migraine symptoms and should not be used to treat migraines.

You say

Diphenhydramine is one of the drugs that most people experience. how about you? Have you ever used diphenhydramine? What was the reason? Have you experienced any side effects? If you wish, you can share this experience and comments with us in the “Post a Comment” section. You can also send this article to friends through social networks to learn more about diphenhydramine.

Other sources: Adbenadryl

Warning! This article is for educational purposes only and you should consult your doctor or specialist to use it. more information

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Everything about Diphenhydramine; From how to use to side effects and drug interactions

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